Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115910 | 0.83 | NPC1 (0.65) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL59705 | 0.82 | NPC1 (0.66) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2947575 | 0.81 | MDH1 (0.60) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28837191 | 0.80 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29606712 | 0.80 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2959014 | 0.74 | ALDH1A1 (0.78) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL2951483 | 0.74 | HPGD (0.60) | NPC1RAB9AALDH1A1HPGDTP53 | |
| SCHEMBL2959308 | 0.72 | KMT2A (0.57) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2950872 | 0.72 | NPC1 (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2959991 | 0.71 | KMT2A (0.55) | RAB9AALDH1A1HPGDSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104056278-B | 1,2,4-oxadiazole benzoic acid compounds | PTC 治疗公司 | 2017-01-18 | — | — | CN | disclosed |