Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.64 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59705 | 0.99 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL2947575 | 0.89 | MDH1 (0.60) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL28837191 | 0.88 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL29606712 | 0.88 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL2950872 | 0.88 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL2947496 | 0.86 | MEN1 (0.79) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL2960933 | 0.84 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL2950201 | 0.83 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL28115906 | 0.83 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2957003 | 0.83 | HIF1A (0.72) | NPC1RAB9ASMN1; SMN2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104056278-B | 1,2,4-oxadiazole benzoic acid compounds | PTC 治疗公司 | 2017-01-18 | — | — | CN | disclosed |