SCHEMBL28115976

SCHEMBL28115976

C=C(CCCC)C(=O)OC.C=COC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TSHR P16473 4/20 0.34
CES1 P23141 2/20 0.33
FAAH O00519 1/20 0.33
HPGD P15428 1/20 0.33
CES2 O00748 1/20 0.32
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
LMNA P02545 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570810 0.86 TSHR (0.33) ALDH1A1TSHRCES1HPGDCES2
SCHEMBL28232223 0.84 ALDH1A1 (0.40) ALDH1A1TSHRLMNA
SCHEMBL1298659 0.84 CES1 (0.44) ALDH1A1TSHRCES1CES2POLB
SCHEMBL2991157 0.83 FNTA (0.37) ALDH1A1TSHRCES1HPGDCES2
SCHEMBL3841843 0.83 CES1 (0.39) ALDH1A1TSHRCES1FAAHHPGD
Acetic Acid SCHEMBL28135566 0.83 ALDH1A1 (0.43) ALDH1A1TSHRCES1CES2TP53
SCHEMBL10579259 0.82 TSHR (0.42) ALDH1A1TSHRCES1HPGDCES2
Ethylene SCHEMBL9299137 0.82 CES1 (0.42) ALDH1A1TSHRCES1CES2POLB
Acetic Acid SCHEMBL27955148 0.81 TSHR (0.37) ALDH1A1TSHRCES1HPGDCES2
Acrylic Acid SCHEMBL28099761 0.81 ALOX15 (0.41) ALDH1A1TSHRCES1FAAHHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106536623-B Composition 日本梅克特隆株式会社 2018-11-30 CN disclosed
CN-106536623-A Composition 日本梅克特隆株式会社 2017-03-22 CN disclosed