Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115976 | 0.86 | ALDH1A1 (0.35) | TSHRCES1HPGDALDH1A1CES2 | |
| SCHEMBL1514197 | 0.85 | CES1 (0.42) | TSHRCES1ALDH1A1CES2 | |
| SCHEMBL2991157 | 0.82 | FNTA (0.37) | TSHRCES1HPGDALDH1A1CES2 | |
| SCHEMBL3841843 | 0.81 | CES1 (0.39) | TSHRCES1HPGDALDH1A1CES2 | |
| Acetic Acid SCHEMBL27955148 | 0.80 | TSHR (0.37) | TSHRCES1HPGDALDH1A1CES2 | |
| SCHEMBL7912871 | 0.79 | FAAH (0.47) | TSHRCES1HPGDALDH1A1CES2 | |
| Acrylic Acid SCHEMBL11535018 | 0.78 | TSHR (0.40) | TSHRCES1HPGDALDH1A1CES2 | |
| SCHEMBL322034 | 0.78 | FNTA (0.43) | TSHRCES1ALDH1A1CES2 | |
| Hexane SCHEMBL3257416 | 0.77 | ALDH1A1 (0.44) | TSHRCES1HPGDALDH1A1CES2 | |
| Butane SCHEMBL722315 | 0.77 | ALDH1A1 (0.38) | TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820487-B1 | AQUEOUS SILYLATED POLYMER CURABLE COMPOSITIONS | CROMPTON CORP (US) | 2004-04-14 | — | — | EP | disclosed |
| EP-0820487-A4 | AQUEOUS SILYLATED POLYMER CURABLE COMPOSITIONS | OSI SPECIALTIES INC (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5827922-A | Aqueous silylated polymer curable compositions with tin catalysts | OSI SPECIALTIES, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0820487-A1 | AQUEOUS SILYLATED POLYMER CURABLE COMPOSITIONS | OSi SPECIALTIES LTD. (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1997030120-A1 | AQUEOUS SILYLATED POLYMER CURABLE COMPOSITIONS | OSI SPECIALTIES, INC. (US) | 1997-08-21 | — | — | WO | disclosed |