SCHEMBL28116030

SCHEMBL28116030

Cc1ccc(S(N)(=O)=O)c(CCN)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.56
HTR2A P28223 2/20 0.46
HTR1D P28221 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
PTGES2 Q9H7Z7 4/20 0.40
CA6 P23280 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20478179 0.88 TAAR1 (0.42) TAAR1HTR2AKDM4EALDH1A1CYP1A2
SCHEMBL1806651 0.86 KDM4E (0.41) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL8215092 0.86 CA2 (0.42) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL20478175 0.85 PDIA6 (0.40) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL1806652 0.84 CA2 (0.41) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL38652325 0.84 PTGES2 (0.41) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL3975257 0.84 TAAR1 (0.55) TAAR1HTR2AHTR1DKDM4EALDH1A1
SCHEMBL30239066 0.84 PTGES2 (0.42) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL6712202 0.84 KDM4E (0.41) TAAR1KDM4EALDH1A1CYP1A2MEN1
SCHEMBL1504600 0.84 PTGES2 (0.42) TAAR1KDM4EALDH1A1CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117139-B A kind of enhanced fluorescence probe and preparation method and application 华南理工大学 2018-06-19 CN disclosed
CN-106117139-A A kind of enhancement mode fluorescent probe and preparation method and application 华南理工大学 2016-11-16 CN disclosed