Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239066 | 1.00 | PTGES2 (0.42) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL10431753 | 0.90 | PDIA6 (0.43) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL9820115 | 0.86 | TAAR1 (0.36) | PTGES2ALDH1A1TAAR1POLBMAPT | |
| SCHEMBL1806651 | 0.84 | KDM4E (0.41) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL8215092 | 0.84 | CA2 (0.42) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL28116030 | 0.84 | TAAR1 (0.56) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL755113 | 0.83 | GAA (0.37) | PTGES2KDM4EALDH1A1TAAR1MEN1 | |
| SCHEMBL20478179 | 0.83 | TAAR1 (0.42) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL38652325 | 0.83 | PTGES2 (0.41) | PTGES2KDM4EALDH1A1CA2CA9 | |
| SCHEMBL6712202 | 0.83 | KDM4E (0.41) | PTGES2KDM4EALDH1A1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115321919-B | High-performance machine-made sand concrete and preparation method thereof | 河南金诺混凝土有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115321919-A | High-performance machine-made sand concrete and preparation method thereof | 河南金诺混凝土有限公司 | 2022-11-11 | — | — | CN | claimed |
| EP-0789699-B1 | SPIRO[HETEROCYCLE-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE]-4'-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1999-03-17 | — | — | EP | claimed |
| EP-4424686-A1 | COMPLEXES AND LIGANDS | The General Hospital Corporation (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-112424177-B | One-pot organic pseudo-catalytic C-H activation method for preparing vortioxetine and vortioxetine intermediate | VIO制药公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-109415336-B | MDM2 protein degradation agent | 密执安大学评议会 | 2023-08-29 | — | — | CN | disclosed |
| CN-115321919-B | High-performance machine-made sand concrete and preparation method thereof | 河南金诺混凝土有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115776983-A | Heterocyclic immunomodulators | 北京诺诚健华医药科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115321919-A | High-performance machine-made sand concrete and preparation method thereof | 河南金诺混凝土有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-108368083-B | Heteroaryl compounds and their use as therapeutic agents | 东亚首希控股股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113896711-A | Heterocyclic immunomodulators | 北京诺诚健华医药科技有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113788818-A | MDM2 protein degrading agent | 密执安大学评议会 | 2021-12-14 | — | — | CN | disclosed |
| CN-113677664-A | Tricyclic degradants of IKAROS and AIOLOS | C4医药公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-112585139-A | Nalidinone compounds as T cell activators | 百时美施贵宝公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112424177-A | One-pot organic pseudo-catalytic C-H activation method for preparing vortioxetine and vortioxetine intermediate | VIO制药公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-2477968-A1 | N- [2-HYDROXYCARBAMOYL-2- (PIPERAZINYL) ETHYL]BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | Galderma Research & Development (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033009-A1 | N- [2-HYDROXYCARBAMOYL-2- (PIPERAZINYL) ETHYL] BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-03-24 | — | — | WO | disclosed |