SCHEMBL28116067

SCHEMBL28116067

C=CC(=O)Nc1ccc(C(N)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 13/20 0.58
F13A1 P00488 3/20 0.58
TGM1 P22735 3/20 0.58
LMNA P02545 1/20 0.58
TGM3 Q08188 1/20 0.58
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
CDK7 P50613 1/20 0.41
CDK13 Q14004 1/20 0.41
CYP2C19 P33261 1/20 0.41
FYN P06241 1/20 0.40
SRC P12931 1/20 0.40
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20446055 0.83 TGM2 (0.58) TGM2F13A1TGM1LMNATGM3
SCHEMBL20446054 0.83 TGM2 (0.58) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.82 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL1381808 0.80 TGM2 (0.65) TGM2F13A1TGM1LMNATGM3
SCHEMBL23328326 0.77 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL2723385 0.77 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL38661653 0.77 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL2722982 0.77 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL7785803 0.77 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL6481884 0.77 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502847-B Medical devices having homogeneous charge density and methods for making same 庄臣及庄臣视力保护公司 2017-01-18 CN disclosed