Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215132 | 0.82 | LMNA (0.41) | LMNANMT1POLBGAAALDH1A1 | |
| SCHEMBL29016162 | 0.78 | IRAK4 (0.36) | ALOX5AP | |
| SCHEMBL1207566 | 0.73 | — | — | |
| SCHEMBL21023555 | 0.71 | — | — | |
| SCHEMBL1559606 | 0.69 | LMNA (0.54) | LMNANMT1POLBGAAALDH1A1 | |
| SCHEMBL21246184 | 0.68 | LMNA (0.56) | LMNANMT1POLBGAAALDH1A1 | |
| SCHEMBL4551051 | 0.67 | FPR2 (0.43) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL4208860 | 0.67 | RAB9A (0.46) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL27467128 | 0.67 | ADORA2A (0.37) | LMNANMT1POLBNPC1RAB9A | |
| SCHEMBL26789513 | 0.66 | LMNA (0.53) | LMNAPOLBGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243101-B | A kind of 1,3,4- thiadiazoles sulfide derivative and its preparation method and application | 浙江工业大学 | 2019-05-24 | — | — | CN | claimed |
| CN-106243101-A | A kind of 1,3,4 thiadiazoles sulfide derivatives and its preparation method and application | 浙江工业大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243101-A | A kind of 1,3,4 thiadiazoles sulfide derivatives and its preparation method and application | 浙江工业大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106212482-A | The application in preparing herbicide of a kind of 1,3,4 thiadiazoles sulfide derivatives | 浙江工业大学 | 2016-12-14 | — | — | CN | disclosed |