Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763752 | 0.81 | NPC1 (0.67) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL13160197 | 0.80 | HDAC3 (0.65) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7917574 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL12763751 | 0.77 | MAPT (0.62) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL28116653 | 0.77 | HDAC3 (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL31030915 | 0.76 | CHEK2 (0.70) | CHEK2 | |
| SCHEMBL7916899 | 0.74 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10737170 | 0.73 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30442918 | 0.73 | KDM4E (0.59) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL31154221 | 0.73 | MEN1 (0.51) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |