Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17316613 | 0.86 | LMNA (0.49) | LMNAHDAC1KMT2AMEN1PKM | |
| SCHEMBL21199265 | 0.84 | SOS1 (0.52) | LMNAHDAC1HDAC7KMT2AMEN1 | |
| SCHEMBL17316771 | 0.82 | CACNA1G (0.50) | LMNAKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL25430551 | 0.82 | PKM (0.47) | LMNAKMT2AMEN1PKMALDH1A1 | |
| SCHEMBL1865930 | 0.82 | LMNA (0.47) | LMNAHDAC1KMT2AMEN1PKM | |
| SCHEMBL17316432 | 0.82 | PKM (0.52) | LMNAHDAC1KMT2AMEN1PKM | |
| SCHEMBL17316381 | 0.82 | LMNA (0.47) | LMNAKMT2AALDH1A1POLB | |
| SCHEMBL17316559 | 0.81 | PKM (0.41) | LMNAKMT2APKMHIF1AALDH1A1 | |
| SCHEMBL17316380 | 0.81 | LMNA (0.47) | LMNAHDAC1KMT2AMEN1PKM | |
| SCHEMBL17316285 | 0.81 | LMNA (0.49) | LMNAHDAC1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |