Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269332 | 0.82 | KMT2A (0.51) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL28271116 | 0.82 | LMNA (0.44) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL25428185 | 0.82 | PKM (0.47) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL28116680 | 0.80 | POLB (0.57) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1866232 | 0.78 | F2 (0.49) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL25226424 | 0.76 | PKM (0.45) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL29049999 | 0.76 | KMT2A (0.51) | KMT2ALMNAALDH1A1MEN1NPC1 | |
| SCHEMBL1857009 | 0.76 | LMNA (0.52) | KMT2ALMNAALDH1A1MEN1NPC1 | |
| SCHEMBL17316371 | 0.74 | LMNA (0.46) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1862274 | 0.74 | KMT2A (0.51) | KMT2ALMNACYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |