Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269332 | 0.80 | KMT2A (0.51) | POLBPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28271116 | 0.80 | LMNA (0.44) | POLBPKMLMNAALDH1A1MEN1 | |
| SCHEMBL28116679 | 0.80 | KMT2A (0.53) | PKMSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL1866232 | 0.76 | F2 (0.49) | POLBPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25226424 | 0.71 | PKM (0.45) | POLBPKMLMNAALDH1A1MEN1 | |
| SCHEMBL28116675 | 0.69 | KMT2A (0.45) | POLBPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28116367 | 0.69 | RECQL (0.52) | PKMSMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL28116300 | 0.69 | HDAC1 (0.47) | POLBPKMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28116296 | 0.69 | RIPK1 (0.60) | POLBPKMLMNAALDH1A1MAPT | |
| SCHEMBL16118387 | 0.69 | KMT2A (0.67) | PKMSMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |