Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693552 | 0.83 | PARP1 (0.52) | MAPK10ARPARP1LMNAENPP1 | |
| SCHEMBL248215 | 0.82 | PARP1 (0.64) | MAPK10ARPARP1LMNAENPP1 | |
| SCHEMBL30801304 | 0.82 | PARP1 (0.64) | MAPK10ARPARP1LMNAENPP1 | |
| SCHEMBL154687 | 0.80 | LMNA (0.49) | MAPK10ARPARP1MAPTLMNA | |
| SCHEMBL4488379 | 0.80 | PARP1 (0.52) | MAPK10ARPARP1MAPTLMNA | |
| SCHEMBL694505 | 0.76 | PARP1 (0.45) | ARPARP1LMNAENPP1KDM4E | |
| SCHEMBL28098683 | 0.76 | CNR1 (0.62) | MAPK10ARPARP1MAPTLMNA | |
| SCHEMBL1513026 | 0.74 | IDO1 (0.65) | MAPK10KIF11KDM4EPDPK1GAA | |
| SCHEMBL14979171 | 0.74 | MEN1 (0.55) | ARPARP1MAPTLMNAENPP1 | |
| SCHEMBL15826381 | 0.71 | KDM4E (0.44) | MAPK10ARKDM4EPDPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232583-A | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2016-12-14 | — | — | CN | disclosed |