Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 11/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28117072 | 0.93 | MEN1 (0.64) | PTGESMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28117528 | 0.90 | CYP1A1 (0.69) | PTGESMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12298231 | 0.88 | CYP1B1 (0.67) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL28117523 | 0.86 | ALOX5 (0.59) | PTGESMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28117525 | 0.86 | MEN1 (0.59) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12297793 | 0.85 | ALOX5 (0.61) | PTGESMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28330115 | 0.84 | PTGS2 (0.73) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12298237 | 0.83 | MEN1 (0.65) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14458591 | 0.83 | ALOX5 (0.62) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1890637 | 0.83 | BRAF (0.62) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220582-B | n, 4-diaryl thiazole-2-amine compound and application thereof as tumor cell proliferation inhibitor | 沈阳药科大学 | 2019-12-10 | — | — | CN | claimed |
| CN-106220582-A | N, 4 diaryl thiazole 2 aminated compoundss and the purposes as tumor cell proliferation inhibitor thereof | 沈阳药科大学 | 2016-12-14 | — | — | CN | claimed |
| CN-106220582-B | n, 4-diaryl thiazole-2-amine compound and application thereof as tumor cell proliferation inhibitor | 沈阳药科大学 | 2019-12-10 | — | — | CN | disclosed |
| CN-106220582-A | N, 4 diaryl thiazole 2 aminated compoundss and the purposes as tumor cell proliferation inhibitor thereof | 沈阳药科大学 | 2016-12-14 | — | — | CN | disclosed |