Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15634991 | 0.91 | ADRA2A (0.39) | STING1TSHRADRA2AADRA1AHDAC3 | |
| SCHEMBL631111 | 0.91 | EGLN1 (0.48) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Chloromethane SCHEMBL3415691 | 0.89 | EGLN1 (0.46) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Cyclohexane SCHEMBL27625968 | 0.85 | LMNA (0.44) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Butane SCHEMBL2855608 | 0.85 | FFAR3 (0.44) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL644646 | 0.82 | TSHR (0.45) | ALDH1A1STING1TSHRADRA2AADRA1A | |
| SCHEMBL2336160 | 0.82 | LMNA (0.56) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| Succinic Acid SCHEMBL29896338 | 0.82 | EGLN1 (0.41) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL28341877 | 0.82 | EGLN1 (0.41) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL3123396 | 0.79 | EGLN1 (0.42) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255509-A | For the succinate prodrug of application in owing to the lactic acidosis of complex I associated injury of Mitochondria or the treatment of drug-induced side effect | 纽维制药有限公司 | 2016-12-21 | — | — | CN | disclosed |