Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 7/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743372 | 0.85 | LMNA (0.71) | LMNADHODHPDE10ATSHRCYP2D6 | |
| SCHEMBL16895273 | 0.82 | LMNA (0.57) | LMNADHODHPDE10ATSHR | |
| SCHEMBL21451029 | 0.82 | LMNA (0.57) | LMNADHODHPDE10ATSHRKDM4E | |
| SCHEMBL3737883 | 0.78 | LMNA (0.54) | LMNADHODHCYP2D6CYP2C19KDM4E | |
| SCHEMBL28250898 | 0.76 | LMNA (0.73) | LMNADHODHPDE10ATSHRPOLB | |
| SCHEMBL27651467 | 0.76 | TAAR1 (0.55) | LMNATSHRPOLBTAAR1KDM4E | |
| SCHEMBL16039610 | 0.73 | PRNP (0.47) | LMNAPDE10ATSHRTAAR1CYP2D6 | |
| SCHEMBL3750345 | 0.73 | DHODH (0.54) | DHODHKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL10467326 | 0.72 | DHODH (0.59) | LMNADHODHPDE10ATSHRCYP2D6 | |
| SCHEMBL28040025 | 0.72 | KDM4E (0.56) | LMNATSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279021-A | One class Antibiotic FR 901228 based on indeno quinolinone skeleton and its preparation method and application | 中国人民解放军第二军医大学 | 2017-01-04 | — | — | CN | disclosed |