SCHEMBL28117832

SCHEMBL28117832

CC1(C)OC(=O)OC1=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
SIRT1 Q96EB6 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
STK17B O94768 1/20 0.38
MAPT P10636 1/20 0.37
CYP1A2 P05177 2/20 0.36
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PIM1 P11309 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118038 0.83 SIRT1 (0.47) ALDH1A1KDM4EHPGDTDP1SIRT1
SCHEMBL28117412 0.81 ALDH1A1 (0.47) ALDH1A1KDM4EL3MBTL1MEN1KMT2A
SCHEMBL28117410 0.80 ALDH1A1 (0.37) ALDH1A1KDM4EHPGDL3MBTL1TDP1
SCHEMBL28117367 0.80 METAP1 (0.46) ALDH1A1MAPTCYP1A2LMNASMN1; SMN2
SCHEMBL28117370 0.80 METAP1 (0.46) ALDH1A1MAPTCYP1A2LMNASMN1; SMN2
SCHEMBL28117931 0.75 ELANE (0.43) ALDH1A1L3MBTL1KMT2AMAOB
SCHEMBL28117883 0.72 ELANE (0.41) L3MBTL1KMT2AMAPTLMNA
SCHEMBL28042997 0.71 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDL3MBTL1TDP1
SCHEMBL1587773 0.69 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDSIRT1MEN1
SCHEMBL6982661 0.68 ITGB3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110078733-B Double-functionalized alkaline ionic liquid catalyst and preparation method and application thereof 中国科学院兰州化学物理研究所苏州研究院 2020-07-24 CN disclosed
CN-103764708-B Photopolymerizable composition, photopolymerizable coating agent, laminate, and polarizing plate 东洋油墨SC控股株式会社 2016-12-14 CN disclosed