Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | STK17B | O94768 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244107 | 0.83 | FLT3 (1.00) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL31061078 | 0.83 | FLT3 (1.00) | FLT3NPC1RAB9AMAPK1TSHR | |
| Benzene SCHEMBL28107977 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL29460209 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL29496924 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL649402 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL5366245 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL155789 | 0.82 | FLT3 (0.74) | FLT3NPC1RAB9AMAPK1TSHR | |
| SCHEMBL28117952 | 0.81 | FLT3 (0.67) | FLT3NPC1RAB9AMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL5981164 | 0.80 | FLT3 (0.71) | FLT3NPC1RAB9AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070212705-A1 | PSEUDOMONAS AERUGINOSA L-D CARBOXYPEPTIDASE A, EXPRESSION AND ACTIVITY | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-13 | — | — | US | claimed |
| WO-2007050513-A2 | PSEUDOMONAS AERUGINOSA L-D CARBOXYPEPTIDASE A, EXPRESSION AND ACTIVITY | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-05-03 | — | — | WO | claimed |
| US-20070212705-A1 | PSEUDOMONAS AERUGINOSA L-D CARBOXYPEPTIDASE A, EXPRESSION AND ACTIVITY | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-13 | — | — | US | disclosed |
| WO-2007050513-A2 | PSEUDOMONAS AERUGINOSA L-D CARBOXYPEPTIDASE A, EXPRESSION AND ACTIVITY | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-05-03 | — | — | WO | disclosed |
| WO-1996016981-A2 | PEPTIDE COMPOUNDS FOR PREVENTION AND/OR TREATMENT OF NO-MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-06 | — | — | WO | disclosed |