Diflubenzuron

Diflubenzuron

SCHEMBL28118261

CCCCO.O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(Cl)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CNR1 P21554 5/20 0.46
GAA P10253 4/20 0.44
PKM P14618 1/20 0.43
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TRPA1 O75762 1/20 0.41
ITGB1 P05556 1/20 0.41
ITGA4 P13612 1/20 0.41
KDM4E B2RXH2 1/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diflubenzuron SCHEMBL18837607 0.87 RAB9A (0.59) RAB9ANPC1MEN1KMT2ACNR1
Diflubenzuron SCHEMBL42416 0.87 RAB9A (0.59) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10712013 0.85 SLC6A3 (0.53) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL9324631 0.85 RAB9A (0.57) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10711203 0.83 RAB9A (0.56) RAB9ANPC1MEN1KMT2ACNR1
Diflubenzuron SCHEMBL8729691 0.83 NPC1 (0.56) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10706436 0.83 HDAC6 (0.46) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10704769 0.83 MEN1 (0.43) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10711195 0.83 SLC6A3 (0.49) RAB9ANPC1MEN1KMT2ACNR1
SCHEMBL10706860 0.82 RAB9A (0.47) RAB9ANPC1MEN1KMT2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106386092-A Method for planting strontium-enriched lettuce 马山盛世生态种养专业合作社 2017-02-15 CN claimed
CN-106386092-A Method for planting strontium-enriched lettuce 马山盛世生态种养专业合作社 2017-02-15 CN disclosed