Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711195 | 0.94 | SLC6A3 (0.49) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10706860 | 0.89 | RAB9A (0.47) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10706436 | 0.89 | HDAC6 (0.46) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10704935 | 0.88 | TRPA1 (0.46) | SLC6A3GAAMAPTNPC1RAB9A | |
| SCHEMBL10703872 | 0.86 | HDAC6 (0.43) | SLC6A3GAAMAPTCNR1NPC1 | |
| Diflubenzuron SCHEMBL28118261 | 0.85 | RAB9A (0.48) | GAAMAPTCNR1NPC1RAB9A | |
| SCHEMBL10714679 | 0.85 | HDAC6 (0.43) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10703856 | 0.84 | NPC1 (0.43) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10702812 | 0.83 | MEN1 (0.43) | SLC6A3GAAMAPTCNR1NPC1 | |
| SCHEMBL10704876 | 0.82 | MEN1 (0.43) | SLC6A3GAAMAPTCNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116729-B1 | BENZOYLUREA COMPOUNDS AND PESTICIDAL COMPOSITIONS COMPRISINGSAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-10-12 | — | — | EP | disclosed |
| US-4710516-A | Insecticidal and acaricidal composition comprising a benzoylurea compound | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-12-01 | — | — | US | disclosed |
| US-4665235-A | INSECTICIDES, MITICIDES, ANTITUMOR AGENTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-05-12 | — | — | US | disclosed |