Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | USP2 | O75604 | 7/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21988061 | 0.86 | CYP1B1 (0.58) | KMT2AMEN1CYP1B1MAPTALDH1A1 | |
| SCHEMBL24713004 | 0.83 | KEAP1 (0.64) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL19872904 | 0.83 | USP2 (0.68) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL14329995 | 0.82 | KEAP1 (0.57) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL16085240 | 0.82 | KEAP1 (0.60) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL12660523 | 0.81 | KEAP1 (0.61) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL20385847 | 0.81 | KEAP1 (0.61) | KEAP1NFE2L2TLR9KMT2AMEN1 | |
| SCHEMBL34474429 | 0.80 | SMN1; SMN2 (0.67) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28463507 | 0.80 | SMN1; SMN2 (0.67) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28798795 | 0.80 | KEAP1 (0.64) | KEAP1NFE2L2TLR9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311488-B | APN inhibitor with fluorescence property and application thereof | SHANDONG UNIVERSITY (CN) | 2017-01-04 | — | — | CN | disclosed |