SCHEMBL28118639

SCHEMBL28118639

O=S(=O)(O)c1ccc2c(S(=O)(=O)O)c(O)c(O)cc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.53
NSD2 O96028 2/20 0.53
DUSP3 P51452 1/20 0.53
PTPN5 P54829 1/20 0.53
PTPN11 Q06124 1/20 0.53
PRMT1 Q99873 2/20 0.49
NT5E P21589 2/20 0.45
CYP2C9 P11712 3/20 0.45
CYP1A2 P05177 3/20 0.45
ALDH1A1 P00352 6/20 0.44
HSD17B10 Q99714 4/20 0.44
CYP2C19 P33261 2/20 0.44
TDP1 Q9NUW8 2/20 0.43
HPGD P15428 2/20 0.43
CYP2D6 P10635 1/20 0.43
HIF1A Q16665 3/20 0.41
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231658 0.86 CASP6 (0.53) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL9350146 0.85 ALDH1A1 (0.52) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL10508205 0.81 NT5E (0.54) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL3908107 0.80 CASP6 (0.50) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL29462031 0.80 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL465086 0.80 CASP6 (0.77) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL30996433 0.79 CYP2D6 (0.66) CASP6NSD2CYP2C9CYP1A2ALDH1A1
SCHEMBL3262066 0.79 CYP2D6 (0.66) CASP6NSD2CYP2C9CYP1A2ALDH1A1
SCHEMBL10408502 0.78 MEN1 (0.47) CASP6NSD2DUSP3PTPN5PTPN11
SCHEMBL18274858 0.78 CASP6 (0.74) CASP6NSD2DUSP3PTPN5PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106187835-A 2,3 dihydroxy naphthlene 1,6 disulfonic acid chemical intermediate synthetic methods 江苏扬农化工集团有限公司 2016-12-07 CN claimed
CN-106187835-A 2,3 dihydroxy naphthlene 1,6 disulfonic acid chemical intermediate synthetic methods 江苏扬农化工集团有限公司 2016-12-07 CN disclosed