Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580142 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL26302 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL123766 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL28190143 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL28436056 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL7065265 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL28266492 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL29866763 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL1012864 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL4983762 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10ALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749135-B | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2019-07-19 | — | — | CN | claimed |
| CN-106279082-B | Substituted furans chalcone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106905340-B | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106279083-B | A kind of furocoumarin analog derivative and preparation method thereof | 浙江大学 | 2019-01-08 | — | — | CN | claimed |
| CN-106243126-B | Substituted furans isoquinolines analog derivative and preparation method thereof | 浙江大学 | 2018-09-18 | — | — | CN | claimed |
| CN-106243121-B | Substituted furan-flavone alcohol derivatives and preparation method thereof | 浙江大学 | 2018-07-13 | — | — | CN | claimed |
| CN-106336417-B | Substituted furans isoflavonoid derivatives and preparation method thereof | 浙江大学 | 2018-07-13 | — | — | CN | claimed |
| CN-106905340-A | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2017-06-30 | — | — | CN | claimed |
| CN-106749135-A | Substituted benzofuran formyl hydrazone analog derivative and preparation method thereof | 浙江大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | claimed |
| CN-106336416-A | Furan flavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | claimed |
| CN-110423228-A | A method of preparing darunavir intermediate | CHENGDU PORTON PHARMACY CO LTD | 2019-11-08 | — | — | CN | disclosed |
| CN-107043385-B | Method for preparing darunavir intermediate | 成都博腾药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109956886-A | (Z)-[(4- methoxyphenyl) hydrazono-] preparation method of ethyl chloroacetate | 连云港恒运药业有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-109400579-A | A kind of Green production method of low cost lenalidomide | 新发药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-107043385-A | Method for preparing darunavir intermediate | 成都博腾药业有限公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | disclosed |