SCHEMBL28118930

SCHEMBL28118930

NCCCCCCCCCC(N)(c1ccc(Nc2ccccc2)cc1)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 5/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
ALOX12 P18054 3/20 0.43
TSHR P16473 3/20 0.43
ALOX15 P16050 2/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
MAPK1 P28482 1/20 0.43
PTGS2 P35354 1/20 0.43
HTR2B P41595 1/20 0.43
KIF11 P52732 6/20 0.42
MAPT P10636 6/20 0.41
CYP3A4 P08684 4/20 0.41
HTT P42858 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HPGD P15428 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28118921 1.00 ALDH1A1 (0.43) ALDH1A1HSD17B10L3MBTL1TDP1ALOX12
SCHEMBL902585 0.84 KIF11 (0.57) KIF11CYP3A4CYP2C9CYP2C19KCNH2
SCHEMBL29674396 0.84 KIF11 (0.57) KIF11CYP3A4CYP2C9CYP2C19KCNH2
SCHEMBL28472455 0.82 KIF11 (0.59) KIF11CYP3A4CYP2C9CYP2C19KCNH2
SCHEMBL28118918 0.81 HTT (0.46) ALDH1A1KIF11MAPTHTTCYP1A2
SCHEMBL3630705 0.76 KIF11 (0.68) KIF11CYP3A4CYP2C9CYP2C19KCNH2
SCHEMBL28118490 0.75 TDP1 (0.37) ALDH1A1HSD17B10L3MBTL1TDP1ALOX12
Octadecylamine SCHEMBL5861110 0.73 DNM1 (0.52) ALDH1A1HSD17B10L3MBTL1TDP1ALOX12
Diphenylamine SCHEMBL3650060 0.73 DNM1 (0.52) ALDH1A1HSD17B10L3MBTL1TDP1ALOX12
SCHEMBL459552 0.72 KIF11 (0.41) TSHRKIF11CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414587-B Rubber composition, tire, amine compounds and age resister 大塚化学株式会社 2019-02-12 CN disclosed
CN-106414587-A Rubber composition, tire, amine compound and anti-aging agent 大塚化学株式会社 2017-02-15 CN disclosed