Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483081 | 0.86 | TDP1 (0.61) | LMNAALDH1A1TDP1L3MBTL1CES2 | |
| SCHEMBL28756606 | 0.83 | NPC1 (0.51) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL10560308 | 0.83 | LMNA (0.57) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL28398882 | 0.81 | CES2 (0.52) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL29291317 | 0.81 | LMNA (0.46) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL6201840 | 0.79 | LMNA (0.74) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL5525568 | 0.79 | CES2 (0.55) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL2122042 | 0.78 | SRC (0.57) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL11749522 | 0.78 | LMNA (0.50) | LMNAALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL5873117 | 0.78 | LMNA (0.50) | LMNAALDH1A1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106348990-B | A method of synthesis 1,2,2- triaryl ethyl ketone and its derivative | 兰州大学 | 2019-10-18 | — | — | CN | claimed |
| CN-106348990-B | A method of synthesis 1,2,2- triaryl ethyl ketone and its derivative | 兰州大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-106348990-A | Method for synthesizing 1,2,2-triaryl ethyl ketone and derivatives thereof | 兰州大学 | 2017-01-25 | — | — | CN | disclosed |