Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291314 | 0.88 | LMNA (0.59) | LMNAALDH1A1CES2CES1SLC6A2 | |
| SCHEMBL29291319 | 0.85 | NPC1 (0.47) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL29291311 | 0.83 | CES2 (0.47) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL28118972 | 0.81 | LMNA (0.50) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL29291318 | 0.81 | CES2 (0.57) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL29291321 | 0.80 | MAPT (0.56) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL6201840 | 0.79 | LMNA (0.74) | LMNAALDH1A1CES2CES1SLC6A2 | |
| SCHEMBL29291313 | 0.78 | CES1 (0.53) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL29291316 | 0.77 | ALDH1A1 (0.44) | LMNAALDH1A1CES2CES1MEN1 | |
| SCHEMBL5525568 | 0.75 | CES2 (0.55) | LMNAALDH1A1CES2CES1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734571-B | Method for synthesizing alpha-F-beta-OH-carbonyl compound | 浙江工业大学 | 2021-11-30 | — | — | CN | disclosed |