Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119343 | 1.00 | LTA4H (0.52) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL12155266 | 0.90 | LTA4H (0.61) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7740145 | 0.90 | LTA4H (0.61) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7740147 | 0.90 | LTA4H (0.61) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL25286512 | 0.89 | LTA4H (0.60) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3501117 | 0.89 | LTA4H (0.60) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL15387431 | 0.89 | LTA4H (0.60) | LTA4HLMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL9716820 | 0.85 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL22911218 | 0.85 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL14450594 | 0.85 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104448295-B | The rapamycin derivative of polyethylene glycol multijaw oligopeptides bonding | 北京键凯科技股份有限公司 | 2018-01-23 | — | — | CN | disclosed |
| CN-103965458-B | Polyethylene glycol-amino acid oligopeptide-dasatinib conjugate and pharmaceutical composition thereof | 天津键凯科技有限公司 | 2017-02-15 | — | — | CN | disclosed |