SCHEMBL7740147

SCHEMBL7740147

CC(C)(C)OC(=O)[C@@H](N)CCC(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.61
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC15A1 P46059 2/20 0.45
SYK P43405 1/20 0.44
LMNA P02545 1/20 0.43
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
SLC7A5 Q01650 1/20 0.42
POLB P06746 1/20 0.41
PSMB5 P28074 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740145 1.00 LTA4H (0.61) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL12155266 1.00 LTA4H (0.61) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
Hydrochloric Acid SCHEMBL15387431 0.99 LTA4H (0.60) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
Hydrochloric Acid SCHEMBL3501117 0.99 LTA4H (0.60) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
Hydrochloric Acid SCHEMBL25286512 0.99 LTA4H (0.60) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL8698981 0.92 LTA4H (0.56) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL28119342 0.90 LTA4H (0.52) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL28119343 0.90 LTA4H (0.52) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL22911218 0.89 LTA4H (0.56) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1
SCHEMBL14450594 0.89 LTA4H (0.56) LTA4HALDH1A1MAPK1L3MBTL1SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 US disclosed
EP-4676472-A2 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF TUMORS AND THE INHIBITION OF CANCER-ASSOCIATED FIBROBLASTS Purdue Research Foundation (US) 2026-01-14 EP disclosed
US-12496292-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2025-12-16 US disclosed
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS UNIV MUENCHEN TECH (DE) 2025-12-11 US disclosed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP disclosed
EP-4561968-A1 SILICON-BASED FLUORIDE ACCEPTOR GROUPS FOR RADIOPHARMACEUTICALS Technische Universität München (DE) 2025-06-04 EP disclosed
EP-4541378-A2 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY Endocyte, Inc. (US) 2025-04-23 EP disclosed
EP-3838298-B1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION (US) 2025-02-26 EP disclosed
EP-3777898-B1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY ENDOCYTE INC (US) 2025-01-01 EP disclosed
US-12178892-B2 Compounds for positron emission tomography PURDUE RESEARCH FOUNDATION (US) 2024-12-31 US disclosed
EP-3656403-B1 PREPARATION PROCESS OF PSMA BINDING LIGAND-LINKER CONJUGATES PURDUE RESEARCH FOUNDATION (US) 2022-05-11 EP disclosed
US-11318121-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2022-05-03 US disclosed
US-20220125958-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY PURDUE RESEARCH FOUNDATION 2022-04-28 US disclosed
US-11298341-B2 PSMA binding ligand-linker conjugates and methods for using PURDUE RESEARCH FOUNDATION (US) 2022-04-12 US disclosed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 US disclosed
US-20220096445-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING PURDUE RESEARCH FOUNDATION 2022-03-31 US disclosed
US-8217050-B2 Adenine derivative as inhibitors of HSP90 for the treatment of cancer CHROMA THERAPEUTICS LIMITED (GB) 2012-07-10 US disclosed
US-6420427-B1 PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY ONO PHARMACEUTICAL CO., LTD. (JP) 2002-07-16 US disclosed
CN-1282319-A Aminobutanoic acid derivatives ONO PHARMACEUTICAL CO (JP) 2001-01-31 CN disclosed
EP-1024134-A1 AMINOBUTANOIC ACID DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11298341-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 LTA4H 2233/4885ALDH1A1 2843/4885MAPK1 4290/4885
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF FOLH1, KLK3, FRS2 LTA4H 3879/4885ALDH1A1 1471/4885MAPK1 1660/4885
US-12496292-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 LTA4H 2233/4885ALDH1A1 2843/4885MAPK1 4290/4885
US-11318121-B2 PSMA binding ligand-linker conjugates and methods for using FOLH1, KLK3, PSMA1 LTA4H 2233/4885ALDH1A1 2843/4885MAPK1 4290/4885
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS MAN2B1, GBA1, SSTR1 LTA4H 3656/4885ALDH1A1 625/4885MAPK1 1647/4885
US-20220096445-A1 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING FOLH1, KLK3, PSMA1 LTA4H 2242/4885ALDH1A1 2959/4885MAPK1 4188/4885
US-12178892-B2 Compounds for positron emission tomography FOLH1, FOLR2, FOLR1 LTA4H 1877/4885ALDH1A1 2485/4885MAPK1 3440/4885
US-20220125958-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY FOLH1, FOLR2, FOLR1 LTA4H 1877/4885ALDH1A1 2485/4885MAPK1 3440/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 LTA4H 3407/4885ALDH1A1 2396/4885MAPK1 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.