Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740147 | 1.00 | LTA4H (0.61) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL12155266 | 1.00 | LTA4H (0.61) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| Hydrochloric Acid SCHEMBL15387431 | 0.99 | LTA4H (0.60) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| Hydrochloric Acid SCHEMBL3501117 | 0.99 | LTA4H (0.60) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| Hydrochloric Acid SCHEMBL25286512 | 0.99 | LTA4H (0.60) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL8698981 | 0.92 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL28119342 | 0.90 | LTA4H (0.52) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL28119343 | 0.90 | LTA4H (0.52) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL22911218 | 0.89 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL14450594 | 0.89 | LTA4H (0.56) | LTA4HALDH1A1MAPK1L3MBTL1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541649-A | Preparation method of glutamic acid-5-benzyl ester-1-tert-butyl ester hydrochloride | GL BIOCHEM (SHANGHAI) LTD | 2016-05-04 | — | — | CN | claimed |
| CN-113677400-B | Dual mode radiotracer and therapeutic agent that bind PSMA | 慕尼黑工业大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-116675730-A | Dual mode radiotracer and therapeutic agent that bind PSMA | 慕尼黑工业大学 | 2023-09-01 | — | — | CN | disclosed |
| EP-3127604-B1 | PROCESS FOR THE PREPARATION OF LYSIN-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-08-22 | — | — | EP | disclosed |
| US-20180099934-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | On Target Laboratories, Inc. | 2018-04-12 | — | — | US | disclosed |
| US-20180029978-A1 | PROCESS FOR MAKING LYSINE-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9802886-B2 | Process for making lysine-glutamic acid dipeptide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2017-10-31 | — | — | US | disclosed |
| EP-2849882-B1 | LYSIN-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2017-06-14 | — | — | EP | disclosed |
| US-20170057912-A1 | PROCESS FOR MAKING LYSINE-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2017-03-02 | — | — | US | disclosed |
| EP-3127604-A1 | LYSIN-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2017-02-08 | — | — | EP | disclosed |
| CN-104271227-A | Lysin-glutamic acid dipeptide derivatives | HOFFMANN LA ROCHE | 2015-01-07 | — | — | CN | disclosed |
| WO-2013171135-A1 | LYSIN-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-11-21 | — | — | WO | disclosed |
| EP-2664374-A1 | Lysin-glutamic acid dipeptide derivatives | F. Hoffmann-La Roche AG (CH) | 2013-11-20 | — | — | EP | disclosed |
| US-7888348-B2 | 7-membered ring compound and method of production and pharmaceutical application thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-02-15 | — | — | US | disclosed |
| US-7888348-B2 | 7-membered ring compound and method of production and pharmaceutical application thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20090111796-A1 | 7-membered ring compound and method of production and pharmaceutical application thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090111796-A1 | 7-membered ring compound and method of production and pharmaceutical application thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-6420427-B1 | PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1024134-A1 | AMINOBUTANOIC ACID DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-5919769-A | ANTIINFLAMMATORY AGENT | KANEBO, LTD (JP) | 1999-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099934-A1 | PSMA-TARGETED NIR DYES AND THEIR USES | FOLH1, KLK3, PSMA6 | LTA4H 3263/4885ALDH1A1 477/4885MAPK1 4730/4885 |
| US-20090111796-A1 | 7-membered ring compound and method of production and pharmaceutical application thereof | CMA1, CPA3, SI | LTA4H 219/4885ALDH1A1 1889/4885MAPK1 3456/4885 |
| US-20180029978-A1 | PROCESS FOR MAKING LYSINE-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | GLUL, ASNS, QPCT | LTA4H 475/4885ALDH1A1 2242/4885MAPK1 1610/4885 |
| US-20170057912-A1 | PROCESS FOR MAKING LYSINE-GLUTAMIC ACID DIPEPTIDE DERIVATIVES | GLUL, ASNS, QPCT | LTA4H 475/4885ALDH1A1 2242/4885MAPK1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.