Formic Acid

Formic Acid

SCHEMBL28119412

Fc1ccccc1F.O=C(O)c1cc(F)ccc1F.O=CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.53
CES1 P23141 4/20 0.53
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.44
ALDH1A1 P00352 3/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
FABP4 P15090 4/20 0.42
FABP5 Q01469 3/20 0.42
MAOB P27338 1/20 0.42
ALB P02768 2/20 0.42
ACMSD Q8TDX5 2/20 0.41
LMNA P02545 3/20 0.40
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
ALOX15 P16050 1/20 0.40
NOTUM Q6P988 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28119411 0.91 CES2 (0.59) CES2CES1KEAP1NFE2L2ALDH1A1
SCHEMBL115334 0.85 CES2 (0.71) CES2CES1KEAP1ALDH1A1GAA
SCHEMBL29798953 0.83 CES2 (0.68) CES2CES1KEAP1ALDH1A1GAA
SCHEMBL28742361 0.83 CES2 (0.68) CES2CES1KEAP1ALDH1A1GAA
Formic Acid SCHEMBL27278411 0.75 CES2 (0.48) CES2CES1NFE2L2ALDH1A1
Formic Acid SCHEMBL27369258 0.74 CES2 (0.48) CES2CES1NFE2L2ALDH1A1GAA
SCHEMBL31585927 0.74 ACMSD (0.53) CES2CES1KEAP1ALDH1A1GAA
SCHEMBL20601776 0.74 ACMSD (0.53) CES2CES1KEAP1ALDH1A1GAA
SCHEMBL29367263 0.73 CES2 (0.59) CES2CES1KEAP1NFE2L2ALDH1A1
SCHEMBL333382 0.73 CES2 (0.59) CES2CES1KEAP1NFE2L2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106471635-A Organic hole transmits the p doping cross-linking of body 西门子公司 2017-03-01 CN claimed
CN-106471635-A Organic hole transmits the p doping cross-linking of body 西门子公司 2017-03-01 CN disclosed
CN-106459746-A Sequential functionalization of phosphorescent emitter layers 西门子公司 2017-02-22 CN disclosed
CN-106459744-A Bi-nuclear main group metal phosphorescent emitter 西门子公司 2017-02-22 CN disclosed