SCHEMBL115334

SCHEMBL115334

O=C(O)c1cc(F)ccc1F

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.71
CES1 P23141 3/20 0.71
KEAP1 Q14145 1/20 0.63
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
TTR P02766 2/20 0.49
ALB P02768 2/20 0.49
MEN1 O00255 1/20 0.49
USP2 O75604 1/20 0.49
DHFR P00374 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
LMNA P02545 1/20 0.49
HMGB1 P09429 1/20 0.49
HPGD P15428 1/20 0.49
CXCL12 P48061 1/20 0.49
KMT2A Q03164 1/20 0.49
HIF1A Q16665 1/20 0.49
SLC22A6 Q4U2R8 1/20 0.49
ACMSD Q8TDX5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29798953 0.98 CES2 (0.68) CES2CES1KEAP1KDM4EALDH1A1
SCHEMBL28742361 0.98 CES2 (0.68) CES2CES1KEAP1KDM4EALDH1A1
Formic Acid SCHEMBL28119411 0.90 CES2 (0.59) CES2CES1KEAP1KDM4EALDH1A1
Formic Acid SCHEMBL28119412 0.85 CES2 (0.53) CES2CES1KEAP1KDM4EALDH1A1
SCHEMBL27740945 0.84 KEAP1 (0.56) CES2CES1KEAP1KDM4EALDH1A1
SCHEMBL27673772 0.83 CES2 (0.74) CES2CES1KEAP1ALDH1A1MEN1
SCHEMBL3180092 0.83 CES2 (1.00) CES2CES1KEAP1CA3CA6
SCHEMBL336978 0.83 KEAP1 (0.65) CES2CES1KEAP1KDM4EALDH1A1
SCHEMBL30520290 0.83 KEAP1 (0.65) CES2CES1KEAP1KDM4EALDH1A1
SCHEMBL3062072 0.83 BCL2L1 (0.55) CES2CES1KEAP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-20250347195-A1 OPTIMIZING CO2 GEOSEQUESTRATION WITH RESPONSIVE TRACERS ARAMCO SERVICES COMPANY (US) 2025-11-13 US claimed
CN-119414657-A Fluorine-containing titanium oxide nanoparticle photoresist material, preparation method thereof and application thereof in photoetching technology 山东大学 2025-02-11 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-11994020-B2 Mapping inter-well porosity using tracers with different transport properties SAUDI ARABIAN OIL COMPANY (SA) 2024-05-28 US claimed
CN-114539029-B Synthesis method of 5-fluoro salicylic acid 浙江中欣氟材股份有限公司 2024-04-09 CN claimed
US-20240093598-A1 MAPPING INTER-WELL POROSITY USING TRACERS WITH DIFFERENT TRANSPORT PROPERTIES ARAMCO SERVICES COMPANY (US) 2024-03-21 US claimed
CN-116444454-B N-hydroxy amidine derivative, preparation method and application thereof, and tumor immunotherapy medicament 中国医学科学院医药生物技术研究所 2023-09-12 CN claimed
CN-113880868-B Binuclear rare earth complex crystalline material and preparation method and application thereof 江西师范大学 2023-09-08 CN claimed
CN-116444454-A N-hydroxy amidine derivative, preparation method and application thereof, and tumor immunotherapy medicament 中国医学科学院医药生物技术研究所 2023-07-18 CN claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-20040094297-A1 Method for determining the extent of recovery of materials injected into oil wells or subsurface formations during oil and gas exploration and production CORE LABORATORIES LP 2004-05-20 US claimed
US-6659175-B2 Mixing water, buffers, oxidizers, gels, gelation inhibitors, stabilizer and curing agents with tracers, then pumping the mixtures into bores, withdrawing fluids and measuring concentration of labels; well completion efficiency CORE LABORATORIES, INC. 2003-12-09 US claimed
US-20030006036-A1 Mixing water, buffers, oxidizers, gels, gelation inhibitors, stabilizer and curing agents with tracers, then pumping the mixtures into bores, withdrawing fluids and measuring concentration of labels; well completion efficiency CORE LABORATORIES GLOBAL N.V. (NL) 2003-01-09 US claimed
WO-2002095189-A1 METHOD OF DETERMINING THE EXTENT OF RECOVERY OF MATERIALS INJECTED INTO OIL WELLS CORE LABORATORIES L.P. (US) 2002-11-28 WO claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-H992-H Using copper catalyst in quinoline or n-methyl-2-pyrrolidone OCCIDENTAL CHEMICAL CORPORATION (US) 1991-11-05 US claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 CES2 2351/4885CES1 3786/4885KEAP1 2845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.