SCHEMBL28119413

SCHEMBL28119413

O=C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.[BiH3]

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.67
RXRA P19793 2/20 0.62
RXRB P28702 2/20 0.62
RXRG P48443 1/20 0.62
SRD5A2 P31213 2/20 0.52
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51
P2RX1 P51575 2/20 0.47
GAA P10253 1/20 0.47
MRGPRX4 Q96LA9 2/20 0.45
TACR1 P25103 1/20 0.45
GPR35 Q9HC97 1/20 0.44
SLC6A2 P23975 1/20 0.44
P2RY14 Q15391 1/20 0.44
HDAC3 O15379 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503980 0.98 CES2 (0.70) CES2RXRARXRBRXRGSRD5A2
Hydrochloric Acid SCHEMBL7485970 0.95 CES2 (0.67) CES2RXRARXRBRXRGSRD5A2
SCHEMBL545011 0.93 CES2 (0.62) CES2RXRARXRBRXRGSRD5A2
SCHEMBL17048588 0.89 RXRA (0.72) CES2RXRARXRBRXRGSRD5A2
SCHEMBL12187529 0.87 CES2 (0.57) CES2RXRARXRBRXRGSRD5A2
SCHEMBL15965533 0.87 CES2 (0.57) CES2RXRARXRBRXRGSRD5A2
SCHEMBL3002963 0.86 CES2 (0.55) CES2RXRARXRBRXRGSRD5A2
SCHEMBL30770849 0.85 HCAR1 (0.55) CES2RXRARXRBRXRGSRD5A2
SCHEMBL477824 0.85 CA12 (0.60) CES2RXRARXRBRXRGSRD5A2
SCHEMBL29789615 0.85 CA12 (0.60) CES2RXRARXRBRXRGSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459746-B Sequential functionalization of phosphorescent emitter layers 西门子公司 2019-08-02 CN disclosed
CN-106459746-A Sequential functionalization of phosphorescent emitter layers 西门子公司 2017-02-22 CN disclosed