Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.46 |
| ▸ | PNP | P00491 | 7/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Penciclovir SCHEMBL3494 | 0.84 | TK1 (0.49) | TK1GAAKMT2AHPRT1PNP | |
| Acyclovir SCHEMBL40723 | 0.81 | PNP (0.67) | TK1KMT2AHPRT1PNPUSP2 | |
| Tiviciclovir SCHEMBL15531845 | 0.81 | BLM (0.45) | TK1GAAKMT2AHPRT1PNP | |
| SCHEMBL469372 | 0.80 | KDM4E (0.48) | TK1GAAKMT2AHPRT1PNP | |
| Penciclovir SCHEMBL454089 | 0.80 | HPRT1 (0.47) | TK1KMT2AHPRT1PNPBLM | |
| SCHEMBL769982 | 0.80 | GAA (0.47) | TK1GAAKMT2AHPRT1PNP | |
| Penciclovir SCHEMBL4240103 | 0.80 | HPRT1 (0.47) | TK1KMT2AHPRT1PNPBLM | |
| SCHEMBL133681 | 0.80 | TK1 (0.43) | TK1GAAKMT2AHPRT1PNP | |
| Water SCHEMBL15532449 | 0.79 | TK1 (0.42) | TK1GAAKMT2AHPRT1PNP | |
| SCHEMBL3836263 | 0.79 | TK1 (0.92) | TK1KMT2AHPRT1PNPUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306596-A | Topical application of anti-HSV antibodies | 海德堡免疫疗法有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-106488931-B | Topical application of anti-HSV antibodies | 海德堡免疫疗法有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-106488931-A | Topical application of anti-HSV antibodies | 海德堡免疫疗法有限公司 | 2017-03-08 | — | — | CN | disclosed |