Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28123729

Cc1ccccc1NC(N)=S.S

nearest known ligand 0.96

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
MAPT P10636 3/20 0.63
POLB P06746 2/20 0.63
GAA P10253 1/20 0.63
EPHX1 P07099 2/20 0.58
L3MBTL1 Q9Y468 5/20 0.57
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
HPGD P15428 2/20 0.53
GRIN2D O15399 2/20 0.53
GRIN3B O60391 2/20 0.53
GRIN1 Q05586 2/20 0.53
GRIN2A Q12879 2/20 0.53
GRIN2B Q13224 2/20 0.53
GRIN2C Q14957 2/20 0.53
GRIN3A Q8TCU5 2/20 0.53
SIGMAR1 Q99720 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
PABPC1 P11940 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29998429 0.98 ALDH1A1 (0.66) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL194142 0.98 ALDH1A1 (0.66) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL9725058 0.83 ALDH1A1 (0.58) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL11161401 0.82 ALDH1A1 (0.53) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL7593748 0.82 L3MBTL1 (0.71) ALDH1A1MAPTPOLBGAAL3MBTL1
SCHEMBL1285897 0.82 POLB (0.56) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL5447861 0.82 ALDH1A1 (0.68) ALDH1A1MAPTPOLBGAAL3MBTL1
SCHEMBL29838620 0.82 ALDH1A1 (0.68) ALDH1A1MAPTPOLBGAAL3MBTL1
Allylthiourea SCHEMBL3416269 0.81 ALDH1A1 (0.53) ALDH1A1MAPTPOLBGAAEPHX1
SCHEMBL1276741 0.80 L3MBTL1 (0.70) ALDH1A1MAPTEPHX1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108690384-A Actinic-radiation curable composition, cured coating film and laminated body DIC株式会社 2018-10-23 CN disclosed
CN-106414039-A Three-dimensional object and method of forming the same 株式会社理光 2017-02-15 CN disclosed