SCHEMBL7593748

SCHEMBL7593748

NC(=S)Nc1ccccc1NC(N)=S

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.71
ALDH1A1 P00352 8/20 0.61
HSD17B10 Q99714 2/20 0.61
TP53 P04637 1/20 0.61
TYR P14679 1/20 0.61
TSHR P16473 1/20 0.61
TAS2R38 P59533 1/20 0.61
GAA P10253 5/20 0.59
KDM4E B2RXH2 4/20 0.59
KMT2A Q03164 3/20 0.59
MAPT P10636 3/20 0.59
MEN1 O00255 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
CYP1A2 P05177 3/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
ALOX12 P18054 1/20 0.55
CYP2C19 P33261 1/20 0.55
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9082911 0.91 L3MBTL1 (0.61) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL1116302 0.85 L3MBTL1 (0.61) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL1116321 0.85 L3MBTL1 (0.61) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL9700604 0.85 ALDH1A1 (0.63) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL2315522 0.84 L3MBTL1 (0.59) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL194142 0.84 ALDH1A1 (0.66) L3MBTL1ALDH1A1TSHRGAAKDM4E
SCHEMBL10665419 0.84 L3MBTL1 (0.59) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL2357864 0.84 L3MBTL1 (1.00) L3MBTL1ALDH1A1HSD17B10TP53TYR
SCHEMBL29998429 0.84 ALDH1A1 (0.66) L3MBTL1ALDH1A1TSHRGAAKDM4E
SCHEMBL31022673 0.84 L3MBTL1 (1.00) L3MBTL1ALDH1A1HSD17B10TP53TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252172-A2 COMPOUND COMPRISING A PEPTIDE MOIETY AND AN ORGANO-SILANE MOIETY VBC-Genomics Bioscience Research GmbH (AT) 2002-10-30 EP claimed
EP-1250344-A2 COMPOUND COMPRISING A NUCLEIC ACID MOIETY AND AN ORGANO-SILANE MOIETY VBC-Genomics Bioscience Research GmbH (AT) 2002-10-23 EP claimed
WO-2001046214-A2 COMPOUND COMPRISING A NUCLEIC ACID MOIETY AND AN ORGANO-SILANE MOIETY VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO claimed
WO-2001046213-A2 COMPOUND COMPRISING A PEPTIDE MOIETY AND AN ORGANO-SILANE MOIETY. VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO claimed
EP-1110967-A1 Compound comprising a biomolecule moiety and an organo-silane moiety LION Bioscience AG (DE) 2001-06-27 EP claimed
JP-56081506-A None JP disclosed
JP-52117427-A None JP disclosed
EP-1252172-A2 COMPOUND COMPRISING A PEPTIDE MOIETY AND AN ORGANO-SILANE MOIETY VBC-Genomics Bioscience Research GmbH (AT) 2002-10-30 EP disclosed
EP-1250344-A2 COMPOUND COMPRISING A NUCLEIC ACID MOIETY AND AN ORGANO-SILANE MOIETY VBC-Genomics Bioscience Research GmbH (AT) 2002-10-23 EP disclosed
WO-2001046214-A2 COMPOUND COMPRISING A NUCLEIC ACID MOIETY AND AN ORGANO-SILANE MOIETY VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO disclosed
WO-2001046213-A2 COMPOUND COMPRISING A PEPTIDE MOIETY AND AN ORGANO-SILANE MOIETY. VBC-GENOMICS BIOSCIENCE RESEARCH GMBH (AT) 2001-06-28 WO disclosed
EP-1110967-A1 Compound comprising a biomolecule moiety and an organo-silane moiety LION Bioscience AG (DE) 2001-06-27 EP disclosed
EP-0243872-A1 Pesticidal concentrate compositions BEROL NOBEL (SUISSE) S.A. (CH) 1987-11-04 EP disclosed
JP-S5681506-A FUNGICIDAL COMPOSITION FOR AGRICULTURAL AND HORTICULTURAL USE NIPPON SODA CO LTD 1981-07-03 JP disclosed
JP-S52117427-A AGRICULTURAL AND HORTICULTURAL MICROBICIDAL COMPOSITION HOKKO CHEM IND CO LTD 1977-10-01 JP disclosed
US-4048326-A Treatment of helminth infections with substituted 1,2-bis(thioureido)benzene MAY & BAKER LIMITED (EN) 1977-09-13 US disclosed
US-4029813-A Fungicidal compositions containing bisthioureido-benzenes and methods for use thereof NIPPON SODA COMPANY LIMITED (JA) 1977-06-14 US disclosed
US-4029813-A Fungicidal compositions containing bisthioureido-benzenes and methods for use thereof NIPPON SODA COMPANY LIMITED (JA) 1977-06-14 US disclosed
US-4020095-A FUNGICIDES NIPPON SODA COMPANY LIMITED (JA) 1977-04-26 US disclosed
US-4020095-A FUNGICIDES NIPPON SODA COMPANY LIMITED (JA) 1977-04-26 US disclosed