SCHEMBL28123768

SCHEMBL28123768

O=Nc1ccc2c3c(cccc13)CC2

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.52
KDM4E B2RXH2 11/20 0.52
HPGD P15428 9/20 0.52
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
MAPT P10636 6/20 0.52
LMNA P02545 5/20 0.52
GAA P10253 3/20 0.52
SCN2A Q99250 2/20 0.50
HSD17B10 Q99714 3/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
HTT P42858 1/20 0.48
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ATM Q13315 1/20 0.43
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516669 0.75 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL11516668 0.75 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL18725829 0.73 CYP11B1 (0.45) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL9912659 0.71 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDKMT2AMAPT
SCHEMBL11775136 0.70 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL1275295 0.70 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL28173917 0.69 KEAP1 (0.50) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL1108433 0.69 ALDH1A1 (0.58) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL3341373 0.68 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5368108 0.68 KDM4E (0.57) ALDH1A1KDM4EHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108700779-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal indicate element 日产化学工业株式会社 2018-10-23 CN disclosed
CN-105339340-B Generated base alkaline agent, the alkali reactive composition containing the generated base alkaline agent and production alkali method 富士胶片和光纯药株式会社 2018-10-12 CN disclosed
CN-108603036-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2018-09-28 CN disclosed
CN-106103585-B Branched fluorinated photopolymerizable object 正交公司 2018-09-21 CN disclosed
CN-106414461-B Borate-based generated base alkaline agent and alkali reactive composition containing the generated base alkaline agent 富士胶片和光纯药株式会社 2018-09-11 CN disclosed
CN-105659120-B Cured film, which is formed, uses composition, oriented material and phase difference material NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-31 CN disclosed
CN-105051133-B Composition for forming cured film, alignment material, and phase difference material 日产化学工业株式会社 2018-08-28 CN disclosed
CN-108368350-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal indicate element 日产化学工业株式会社 2018-08-03 CN disclosed
CN-108368036-A Compounds containing Photoepolymerizationinitiater initiater made of the compound and contain the photosensitive polymer combination of the Photoepolymerizationinitiater initiater 学校法人东京理科大学 2018-08-03 CN disclosed
CN-104755571-B Cured film forms with composition, is orientated material and phase difference material 日产化学工业株式会社 2018-07-13 CN disclosed
CN-107112440-A The lithographic patterning of device 正交公司 2017-08-29 CN disclosed
CN-107109050-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal represent element 日产化学工业株式会社 2017-08-29 CN disclosed
CN-104903785-B Method for manufacturing substrate having liquid crystal alignment film for horizontal electric field drive type liquid crystal display element 日产化学工业株式会社 2017-08-15 CN disclosed
CN-107001583-A Photocurable and thermosetting resin composition, cured product, and laminate 株式会社钟化 2017-08-01 CN disclosed
CN-107003577-A The driving liquid crystal of transverse electric field represents that element is manufactured with composition with liquid crystal orientation film, used the liquid crystal orientation film and its manufacture method of said composition and the liquid crystal with liquid crystal orientation film to represent element and its manufacture method 日产化学工业株式会社 2017-08-01 CN disclosed
CN-105324407-B Active energy ray-curable composition 株式会社钟化 2017-07-28 CN disclosed
CN-104817801-B Inorganic-organic Hybrid Material and the optical material and inorganic-organic composite composition for having used the Inorganic-organic Hybrid Material 日本化成株式会社 2017-07-18 CN disclosed
CN-104603650-B It is orientated manufacture method, orientation material, the manufacture method of phase difference material and the phase difference material of material 日产化学工业株式会社 2017-06-06 CN disclosed
CN-106795275-A Actinic-radiation curable composition 株式会社钟化 2017-05-31 CN disclosed
CN-106661336-A Liquid Crystal Alignment Agent, Liquid Crystal Alignment Film, And Liquid Crystal Display Element 日产化学工业株式会社 2017-05-10 CN disclosed