Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144065 | 0.86 | LMNA (0.41) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL28365390 | 0.82 | CYP2A6 (0.56) | RAB9AALDH1A1PDE4APDE4CPDE4D | |
| SCHEMBL3294386 | 0.79 | TSHR (0.46) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL28207101 | 0.75 | NPC1 (0.42) | RAB9AELANENPC1L3MBTL1 | |
| SCHEMBL6714829 | 0.74 | ERN1 (0.54) | RAB9AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12481395 | 0.74 | F7 (0.39) | RAB9AMEN1KMT2AELANEALDH1A1 | |
| SCHEMBL17598049 | 0.74 | ERN1 (0.42) | RAB9AMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL58442 | 0.73 | MEN1 (1.00) | RAB9AMEN1KMT2AASIC3ALDH1A1 | |
| SCHEMBL25390143 | 0.72 | RAB9A (0.57) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5945940 | 0.71 | MEN1 (0.94) | RAB9AMEN1KMT2AASIC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459036-A | Process of preparing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3h-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine | 艾科尔公司 | 2017-02-22 | — | — | CN | disclosed |