SCHEMBL28124158

SCHEMBL28124158

N=C=O.N=C=O.OC1CCOC1O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28140494 1.00 THRB (0.31) THRBLMNA
SCHEMBL465403 0.84
SCHEMBL15521236 0.84
SCHEMBL640109 0.84
SCHEMBL7885066 0.84
SCHEMBL1503719 0.84
SCHEMBL26968767 0.84
SCHEMBL27993104 0.82
Bicarbonate SCHEMBL28459299 0.80 MAPK1 (0.30) LMNA
Acrylic Acid SCHEMBL28849233 0.71 LMNA (0.42) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106641482-A Compound pipeline and preparation process thereof 中国科学院兰州化学物理研究所 2017-05-10 CN claimed
CN-106641482-A Compound pipeline and preparation process thereof 中国科学院兰州化学物理研究所 2017-05-10 CN disclosed