Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465403 | 0.89 | — | — | |
| SCHEMBL640109 | 0.89 | — | — | |
| SCHEMBL1503719 | 0.89 | — | — | |
| SCHEMBL15521236 | 0.89 | — | — | |
| SCHEMBL7885066 | 0.89 | — | — | |
| SCHEMBL26968767 | 0.89 | — | — | |
| SCHEMBL27993104 | 0.86 | — | — | |
| Acrylic Acid SCHEMBL28849233 | 0.84 | LMNA (0.42) | LMNA | |
| SCHEMBL28140494 | 0.80 | THRB (0.31) | LMNA | |
| SCHEMBL28124158 | 0.80 | THRB (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110495040-B | Electrolyte solution, electrochemical device, secondary battery, and module | 大金工业株式会社 | 2022-11-01 | — | — | CN | disclosed |
| CN-110326150-B | Nonaqueous electrolyte solution and electricity storage device | 三菱化学株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-109643826-B | Electrolyte solution, electrochemical device, secondary battery, and module | 大金工业株式会社 | 2022-03-15 | — | — | CN | disclosed |
| CN-113903997-A | Electrolyte solution, electrochemical device, secondary battery, and module | 大金工业株式会社 | 2022-01-07 | — | — | CN | disclosed |
| CN-107408734-B | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2020-08-18 | — | — | CN | disclosed |