SCHEMBL28124309

SCHEMBL28124309

CCc1c(C)cc(O)c(O)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
GAA P10253 3/20 0.42
MAOB P27338 2/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
MCL1 Q07820 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GFER P55789 1/20 0.35
APP P05067 1/20 0.35
KDM4E B2RXH2 4/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
PDE10A Q9Y233 1/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28122020 0.88 ALDH1A1 (0.42) ALDH1A1MAPTGAAMAOBSELL
SCHEMBL27539329 0.83 ALDH1A1 (0.38) ALDH1A1MAPTGAAMAOBSELL
SCHEMBL3676098 0.83 BACE1 (0.37) ALDH1A1MAPTGAASELLSELP
SCHEMBL5677858 0.80 SELL (0.40) ALDH1A1MAPTMAOBSELLSELP
SCHEMBL5677801 0.78 SELL (0.39) ALDH1A1MAPTMAOBSELLSELP
SCHEMBL11584902 0.77 NOS3 (0.41) ALDH1A1MAPTGAAHSD17B10KDM4E
SCHEMBL5676441 0.76 SELL (0.40) ALDH1A1MAPTMAOBSELLSELP
SCHEMBL27781848 0.76 ESR1 (0.41) ALDH1A1MAPTMAOBSELLSELP
SCHEMBL9847329 0.75 ALDH1A1 (0.45) ALDH1A1MAPTGAASELLSELP
SCHEMBL13736318 0.74 ACHE (0.39) ALDH1A1MAPTGAAMAOBSELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109233726-A IPDI trimerization figure Aqueous Polyurethane Adhesives and preparation method thereof 南京理工大学 2019-01-18 CN claimed
CN-108047751-B A kind of band ester group azo dispersion dyes serialization coupling process 沈阳化工研究院有限公司 2019-11-22 CN disclosed
CN-106674471-B A kind of thermoplastic polyurethane elastomer and preparation method thereof, purposes and product 万华化学集团股份有限公司 2019-09-03 CN disclosed
CN-105778783-B A kind of rapid curing two-component adhesive composition of the promotor containing microencapsulation 广东恒大新材料科技有限公司 2019-05-17 CN disclosed
CN-109233726-A IPDI trimerization figure Aqueous Polyurethane Adhesives and preparation method thereof 南京理工大学 2019-01-18 CN disclosed
CN-108395850-A Adhesive, two-component adhesive containing same, bonding method and combination 南通德恒光电科技有限公司 2018-08-14 CN disclosed
CN-108047751-A A kind of band ester group azo dispersion dyes serialization coupling process 沈阳化工研究院有限公司 2018-05-18 CN disclosed
CN-105647423-B A kind of double-deck amine type accelerator microcapsules and preparation method thereof 广东恒大新材料科技有限公司 2017-11-14 CN disclosed
CN-107141437-A A kind of thermoplastic polyurethane material of controllable crystallization and preparation method thereof 万华化学集团股份有限公司 2017-09-08 CN disclosed
CN-106674471-A Thermoplastic polyurethane elastomer and preparation method, application and product thereof 万华化学集团股份有限公司 2017-05-17 CN disclosed
CN-106634499-A Preparation method of transparent anionic aqueous polyurethane polymer high-light coating 上海英诺威新材料科技有限公司 2017-05-10 CN disclosed