Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 2/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192991 | 0.91 | CHRM1 (0.33) | CHRM2CHRM1CHRM3SLC6A1SLC6A11 | |
| SCHEMBL30772071 | 0.83 | SLC6A1 (0.37) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL28124713 | 0.81 | PRKCA (0.33) | LMNATSHRPRKCAPOLBGAA | |
| SCHEMBL19959156 | 0.79 | CHRNB2 (0.40) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL27417189 | 0.78 | CHRM2 (0.34) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL27504346 | 0.78 | SLC6A1 (0.40) | CHRNB2CHRNA4SLC6A1LMNASLC6A11 | |
| SCHEMBL27744409 | 0.78 | SLC6A1 (0.40) | CHRNB2CHRNA4SLC6A1LMNASLC6A11 | |
| SCHEMBL27657052 | 0.78 | SLC6A1 (0.40) | CHRNB2CHRNA4SLC6A1LMNASLC6A11 | |
| SCHEMBL23364687 | 0.76 | CHRNB2 (0.40) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL28759826 | 0.75 | KMT2A (0.41) | CHRNB2CHRNA4SMN1; SMN2KMT2ACPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459034-A | Quinolone derivatives as fibroblast growth factor receptor inhibitors | 普林斯匹亚生物制药公司 | 2017-02-22 | — | — | CN | disclosed |