SCHEMBL2812474

SCHEMBL2812474

CC(=O)CC(=O)OOC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.57
GAA P10253 2/20 0.57
SI P14410 2/20 0.57
MGAM2 Q2M2H8 2/20 0.57
ALDH1A1 P00352 6/20 0.40
TSHR P16473 5/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 2/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609208 0.91 MGAM (0.67) MGAMGAASIMGAM2ALDH1A1
SCHEMBL9436391 0.80 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8364037 0.78
Propionic Acid SCHEMBL28557464 0.75 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL29071013 0.75 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL18832117 0.75 PHF8 (0.54) MGAMGAASIMGAM2ALDH1A1
SCHEMBL727178 0.75 ALDH1A1 (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL25442 0.74
SCHEMBL11463457 0.74
SCHEMBL9280063 0.74 MGAM (0.60) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072952-B Aqueous polymer dispersion and process for producing the same 陶氏环球技术有限责任公司 2022-03-08 CN disclosed
CN-101821308-B Crosslinkable, foamed polyester-polyurethane (hybrid) resin molding compositions with foaming properties for closed mold applications CRAY VALLEY LTD 2013-10-09 CN disclosed
US-8497316-B2 Crosslinkable and foaming polyester-polyurethane (hybrid) resin moulding compositions, with foaming characteristics for closed mould applications CCP COMPOSITES UK LTD (GB) 2013-07-30 US disclosed
US-20100239847-A1 Crosslinkable and Foaming Polyester-Polyurethane (Hybrid) Resin Moulding Compositions, with Foaming Characteristics for Closed Mould Applications U.S. BANK TRUSTEES LIMITED (GB) 2010-09-23 US disclosed
CN-101821308-A Crosslinkable, foamed polyester-polyurethane (hybrid) resin molding compositions with foaming properties for closed mold applications CRAY VALLEY LTD 2010-09-01 CN disclosed
EP-2201056-A1 CROSSLINKABLE AND FOAMING POLYESTER-POLYURETHANE (HYBRID) RESIN MOULDING COMPOSITIONS, WITH FOAMING CHARACTERISTICS FOR CLOSED MOULD APPLICATIONS Cray Valley Ltd (GB) 2010-06-30 EP disclosed
WO-2009046902-A1 CROSSLINKABLE AND FOAMING POLYESTER-POLYURETHANE (HYBRID) RESIN MOULDING COMPOSITIONS, WITH FOAMING CHARACTERISTICS FOR CLOSED MOULD APPLICATIONS CRAY VALLEY LTD (GB) 2009-04-16 WO disclosed
EP-2048172-A1 Crosslinkable and foaming polyester-polyurethane (hybrid) resin moulding compositions, with foaming characteristics for closed mould applications CRAY VALLEY LTD (GB) 2009-04-15 EP disclosed