SCHEMBL727178

SCHEMBL727178

C=C(C)C(=O)OOC(=O)CC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MGAM O43451 2/20 0.48
GAA P10253 2/20 0.48
SI P14410 2/20 0.48
MGAM2 Q2M2H8 2/20 0.48
THRB P10828 1/20 0.41
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5495758 0.89 TSHR (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL609208 0.83 MGAM (0.67) ALDH1A1MGAMGAASIMGAM2
SCHEMBL623936 0.81 MGAM (0.43) ALDH1A1MGAMGAASIMGAM2
SCHEMBL2215339 0.80 ALDH1A1 (0.61) ALDH1A1THRBTSHRTDP1
SCHEMBL727177 0.79 ALDH1A1 (0.50) ALDH1A1MGAMGAASIMGAM2
SCHEMBL2853463 0.78 ALDH1A1 (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL6292365 0.78 MGAM (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28482825 0.77 ALDH1A1 (0.48) ALDH1A1MGAMGAASIMGAM2
SCHEMBL5143369 0.77 MGAM (0.39) ALDH1A1MGAMGAASIMGAM2
SCHEMBL7740516 0.77 THRB (0.55) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267088-A1 COSMETIC COMPOSITION COMPRISING A COPOLYMER BASED ON ACETOACETATE FUNCTIONS L'OREAL (FR) 2023-11-01 EP claimed
EP-2475725-B2 REMOVABLE COLOR GEL BASECOAT FOR ARTIFICIAL NAIL COATINGS AND METHODS THEREFORE BRANDCO CND 2020 LLC (US) 2023-08-02 EP claimed
CN-116284554-A Self-dispersing type water-proof oil-proof soil-release treatment agent for spinning 桐乡市钜成涂装科技有限公司 2023-06-23 CN claimed
CN-114437654-B Water-based quick-setting adhesive and preparation method thereof 英创新材料(绍兴)有限公司 2023-06-13 CN claimed
CN-113461875-B Silicon-containing treating agent and preparation and application thereof 福可新材料(上海)有限公司 2023-05-19 CN claimed
CN-113045696-B Zero-additive low-odor polymer latex and preparation method thereof 万华化学集团股份有限公司 2022-09-20 CN claimed
WO-2022136104-A1 COSMETIC COMPOSITION COMPRISING A COPOLYMER BASED ON ACETOACETATE FUNCTIONS L'OREAL (FR) 2022-06-30 WO claimed
CN-114437654-A Water-based quick-setting adhesive and preparation method thereof 英创新材料(绍兴)有限公司 2022-05-06 CN claimed
CN-113494024-A Fluorine-silicon-containing treating agent and preparation and application thereof 福可新材料(上海)有限公司 2021-10-12 CN claimed
CN-113461875-A Silicon-containing treating agent and preparation and application thereof 福可新材料(上海)有限公司 2021-10-01 CN claimed
US-8399537-B2 Compositions and methods for nail coatings CREATIVE NAIL DESIGN, INC. (US) 2013-03-19 US claimed
WO-2012121704-A1 COMPOSITIONS AND METHODS FOR UV-CURABLE COSMETIC NAIL COATINGS CREATIVE NAIL DESIGN, INC. (US) 2012-09-13 WO claimed
US-20110274633-A1 COMPOSITIONS AND METHODS FOR UV-CURABLE COSMETIC NAIL COATINGS COLOMER USA (US) 2011-11-10 US claimed
JP-4746248-B2 2011-08-10 JP claimed
JP-2003533563-A 2003-11-11 JP claimed
EP-1287051-A1 LATEX FORMULATIONS WITH REDUCED YELLOWING Johnson Polymer, Inc. (US) 2003-03-05 EP claimed
US-6455033-B1 ANTIMICROBIAL COMPOSITION; POLYMERIZABLE ACRYLIC MONOMERS; POLYMERIZATION CATALYSTS; MYCONE DENTAL CORP. 2002-09-24 US claimed
US-6355720-B1 ACETOACETOXYALKYL (METH)ACRYLATE MONOMER; AND ALKYL (METH)ACRYLATE, VINYL AROMATIC AND/OR (METH)ACRYLIC ACID MONOMERS; ULTRAVIOLET RADIATION RESISTANCE, DISCOLORATION INHIBITION JOHNSON POLYMER, INC. 2002-03-12 US claimed
WO-2001088002-A1 LATEX FORMULATIONS WITH REDUCED YELLOWING JOHNSON POLYMER, INC. (US) 2001-11-22 WO claimed
US-5962571-A SOLVENT-FREE, CROSSLINKED POLYMER ZENECA RESINS B.V. (NL) 1999-10-05 US claimed