Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28126278 | 0.83 | NR1H2 (0.40) | KDM4ETDP1MEN1KMT2A | |
| SCHEMBL16793935 | 0.78 | BTK (0.47) | ALDH1A1CDK7 | |
| SCHEMBL15094020 | 0.72 | KDM4E (0.42) | KDM4ETDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL3878573 | 0.72 | TSHR (0.58) | KDM4ETDP1ALDH1A1TSHRMEN1 | |
| SCHEMBL15093922 | 0.70 | MGLL (0.51) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2800989 | 0.70 | KMT2A (0.60) | KDM4ETDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL21551100 | 0.70 | KDM4E (0.49) | KDM4ETDP1ALDH1A1TSHRKMT2A | |
| SCHEMBL2802106 | 0.69 | CYP2A13 (0.61) | KDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL3641216 | 0.69 | KDM4E (0.56) | KDM4EALDH1A1 | |
| SCHEMBL20198190 | 0.69 | LMNA (0.59) | KDM4ETDP1ALDH1A1TSHRGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459002-A | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2017-02-22 | — | — | CN | disclosed |