Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659997 | 0.79 | RAB9A (0.49) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3522852 | 0.78 | RAB9A (0.47) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3517357 | 0.78 | RAB9A (0.47) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3522854 | 0.78 | RAB9A (0.47) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10343768 | 0.76 | RAB9A (0.46) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9523119 | 0.74 | MAPT (0.75) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28349630 | 0.74 | ALOX15 (0.46) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL639726 | 0.73 | ALDH1A1 (0.50) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9523126 | 0.72 | MAPT (0.43) | RAB9AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5132341 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1CYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860938-B | The formamidine compound of cyclization method synthesis polynitrogen heterocycle thiadiazoles 5 | 西华大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-104530040-B | Novel method for synthesizing 1,2,3-thiadiazole-5-formamidine compound | 西华大学 | 2017-01-11 | — | — | CN | disclosed |