SCHEMBL28126242

SCHEMBL28126242

CC(Br)c1c[nH]nc1[N+](=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398919 0.71 CYP19A1 (0.36) MAPT
SCHEMBL11561961 0.71
SCHEMBL319993 0.71
SCHEMBL15740565 0.70 MAPT (0.34) MAPT
SCHEMBL43356 0.70 GPR35 (0.38) MAPT
SCHEMBL9279529 0.67 CPA1 (0.40)
SCHEMBL18976164 0.67
SCHEMBL9324324 0.67
SCHEMBL28116330 0.67
SCHEMBL27670018 0.67 MAPT (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096274-A It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease 比奥根MA公司 2018-12-28 CN disclosed
CN-108947913-A It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease 比奥根MA公司 2018-12-07 CN disclosed
CN-106459002-A Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases 比奥根MA公司 2017-02-22 CN disclosed