SCHEMBL43356

SCHEMBL43356

O=[N+]([O-])c1c[nH]nc1[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.38
MAPT P10636 4/20 0.35
CYP3A4 P08684 3/20 0.35
LMNA P02545 2/20 0.35
CYP1A2 P05177 2/20 0.35
TSHR P16473 2/20 0.35
BLM P54132 2/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
HPGD P15428 1/20 0.35
GRIK1 P39086 1/20 0.35
GRIA1 P42261 1/20 0.35
GRIA2 P42262 1/20 0.35
GRIA3 P42263 1/20 0.35
GRIA4 P48058 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIK2 Q13002 1/20 0.35
GRIK3 Q13003 1/20 0.35
GRIN2B Q13224 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324324 0.77
SCHEMBL319993 0.77
SCHEMBL18976164 0.77
SCHEMBL28116330 0.77
SCHEMBL11561961 0.77
Hydrochloric Acid SCHEMBL29060489 0.76 MAPT (0.33) MAPTLMNAMEN1KMT2AGALR3
SCHEMBL25433762 0.74
SCHEMBL21544010 0.74
SCHEMBL7760580 0.74
SCHEMBL3585568 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer MITOCHON PHARMACEUTICALS, INC. (US) 2026-04-23 US claimed
EP-4724455-A1 MULTIVALENT BINDING UNIT MODIFIED DIDEOXYNUCLEOTIDE TRIPHOSPHATES AND METHODS OF MAKING AND USING THE SAME ILLUMINA, INC. (US) 2026-04-15 EP claimed
US-12590976-B2 Detection method using both fluorescence and chemiluminescence labels ACCESS MEDICAL SYSTEMS, LTD. (US) 2026-03-31 US claimed
US-12570716-B2 Anti-dinitrophenol chimeric antigen receptors SEATTLE CHILDREN'S HOSPITAL (US) 2026-03-10 US claimed
EP-4306167-B1 INDUCED EXPRESSION OF BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) FOR TREATMENT OF NEUROMUSCULAR, NEURODEGENERATIVE, AUTOIMMUNE, DEVELOPMENTAL AND/OR METABOLIC DISEASES MITOCHON PHARMACEUTICALS INC (US) 2025-12-24 EP claimed
EP-4657067-A2 MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES, SUCH AS HISTAMINE President And Fellows Of Harvard College (US) 2025-12-03 EP claimed
US-20250354204-A1 AUTOMATED RNA DETECTION USING LABELED 2'-O-METHYL RNA OLIGONUCLEOTIDE PROBES AND SIGNAL AMPLIFICATION SYSTEMS VENTANA MED SYST INC (US) 2025-11-20 US claimed
WO-2025227129-A2 DELIVERY VEHICLES COMPRISING PROGLUCAGON DERIVED POLYPEPTIDES AND ANABOLIC POLYPEPTIDES AND USES THEREOF STARROCK PHARMA LLC (US) 2025-10-30 WO claimed
EP-4638775-A1 ASSAY METHODS AND KITS Meso Scale Technologies, LLC (US) 2025-10-29 EP claimed
WO-2025217089-A1 ODORIZED FLUIDS AND METHODS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2025-10-16 WO claimed
EP-2444806-A2 Haptens, hapten conjugates, compositions thereof and method for their preparation and use Ventana Medical Systems, Inc. (US) 2012-04-25 EP claimed
EP-2444807-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE Ventana Medical Systems, Inc. (US) 2012-04-25 EP claimed
EP-2130821-B1 Derivatives of 3,4,5-trinitropyrazole, their preparation and the energetic compositions containing them SME (FR) 2011-09-21 EP claimed
EP-2155688-A2 DINITROPYRAZOLE DERIVATIVES, THEIR PREPARATION, AND ENERGETIC COMPOSITIONS COMPRISING THEM. SNPE Matériaux Energétiques (FR) 2010-02-24 EP claimed
EP-2130821-A1 Derivatives of 3,4,5-trinitropyrazole, their preparation and the energetic compositions containing them SNPE Matériaux Energétiques (FR) 2009-12-09 EP claimed
US-20090186931-A1 Dinitropyrazole derivatives, their preparation, and energetic compositions comprising them ARIANEGROUP SAS (FR) 2009-07-23 US claimed
EP-2078197-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE Ventana Medical Systems, Inc. (US) 2009-07-15 EP claimed
WO-2008152525-A2 DINITROPYRAZOLE DERIVATIVES, THEIR PREPARATION, AND ENERGETIC COMPOSITIONS COMPRISING THEM. SNPE MATERIAUX ENERGETIQUES (FR) 2008-12-18 WO claimed
WO-2008063378-A9 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MED SYST INC (US) 2008-07-31 WO claimed
WO-2008063378-A2 HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE VENTANA MEDICAL SYSTEMS, INC. (US) 2008-05-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570716-B2 Anti-dinitrophenol chimeric antigen receptors CD2, CD2BP2, LY96 GPR35 1746/4885MAPT 2236/4885CYP3A4 4191/4885
US-12590976-B2 Detection method using both fluorescence and chemiluminescence labels CD14, FLT4, FLT1 GPR35 3479/4885MAPT 1381/4885CYP3A4 3246/4885
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer DNPH1, SLC5A2, DNPEP GPR35 2262/4885MAPT 1766/4885CYP3A4 149/4885
US-20090186931-A1 Dinitropyrazole derivatives, their preparation, and energetic compositions comprising them NQO2, HRH4, NFE2L2 GPR35 1027/4885MAPT 3611/4885CYP3A4 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.