Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169221 | 0.89 | FABP5 (0.49) | MAPTSMN1; SMN2KMT2AFABP5LMNA | |
| SCHEMBL11717170 | 0.86 | HTR1A (0.44) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7362604 | 0.86 | CYP1A2 (0.42) | MAPTSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10439987 | 0.83 | HSD17B10 (0.46) | SMN1; SMN2KMT2ASSTR4IDO1FABP5 | |
| SCHEMBL30511914 | 0.82 | PTPN1 (0.51) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL13434056 | 0.82 | PTPN1 (0.51) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL10440111 | 0.82 | TYMS (0.46) | MAPTSMN1; SMN2KMT2ARAB9ASSTR4 | |
| SCHEMBL28195451 | 0.82 | CYP19A1 (0.48) | MAPTSMN1; SMN2KMT2ANPC1FABP5 | |
| SCHEMBL27789594 | 0.81 | KDM4E (0.46) | MAPTSMN1; SMN2KMT2AIDO1LMNA | |
| SCHEMBL29029709 | 0.80 | AAK1 (0.46) | SMN1; SMN2KMT2ANPC1RAB9ASSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115887458-A | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicine or reagent for promoting hepatocyte proliferation | 集美大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115887458-B | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicines or reagents for promoting liver cell proliferation | 集美大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-115887458-B | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicines or reagents for promoting liver cell proliferation | 集美大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-115887458-B | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicines or reagents for promoting liver cell proliferation | 集美大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-115887458-A | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicine or reagent for promoting hepatocyte proliferation | 集美大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115887458-A | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicine or reagent for promoting hepatocyte proliferation | 集美大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115887458-A | Application of 4-hydroxy-2-quinoline carboxylic acid ethyl ester in preparation of medicine or reagent for promoting hepatocyte proliferation | 集美大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-110282902-A | A kind of environment-friendly type compounding naphthalene series high-efficiency water-reducing agent and preparation method thereof | 深圳市振惠通混凝土有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-104045599-B | The preparation method of 2- amino-3-aryl quinoline | 江西师范大学 | 2019-03-26 | — | — | CN | disclosed |
| CN-106432073-A | 6-bromo-4-chloroquinoline preparation method | 上海再启生物技术有限公司 | 2017-02-22 | — | — | CN | disclosed |