Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717170 | 0.87 | HTR1A (0.44) | CYP1A2LOXL2IDO1SSTR4NCF1 | |
| SCHEMBL28195451 | 0.86 | CYP19A1 (0.48) | CYP1A2SMN1; SMN2NPC1MAPTFABP5 | |
| SCHEMBL28126381 | 0.86 | MAPT (0.44) | CYP1A2LOXL2IDO1SSTR4SMN1; SMN2 | |
| SCHEMBL2309532 | 0.81 | CYP1A2 (0.45) | CYP1A2LOXL2IDO1SSTR4NCF1 | |
| SCHEMBL10439987 | 0.81 | HSD17B10 (0.46) | IDO1SSTR4NCF1SMN1; SMN2PTPN1 | |
| SCHEMBL29380815 | 0.80 | NCF1 (0.47) | CYP1A2LOXL2IDO1SSTR4NCF1 | |
| SCHEMBL9035250 | 0.80 | LMNA (0.44) | CYP1A2LOXL2IDO1SSTR4NCF1 | |
| SCHEMBL6631053 | 0.80 | NCF1 (0.47) | CYP1A2LOXL2IDO1SSTR4NCF1 | |
| SCHEMBL13434056 | 0.80 | PTPN1 (0.51) | SSTR4NCF1SMN1; SMN2PTPN1PTPN11 | |
| SCHEMBL30511914 | 0.80 | PTPN1 (0.51) | SSTR4NCF1SMN1; SMN2PTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |
| US-4052212-A | ETHER-ESTER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-10-04 | — | — | US | disclosed |