Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362604 | 0.86 | CYP1A2 (0.42) | CYP1A2SMN1; SMN2LMNANPC1MAPT | |
| SCHEMBL3832725 | 0.84 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2TSHRMAPK1KMT2A | |
| SCHEMBL11717170 | 0.83 | HTR1A (0.44) | CYP1A2SMN1; SMN2LMNANPC1MAPT | |
| SCHEMBL28126381 | 0.82 | MAPT (0.44) | CYP1A2SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL2309532 | 0.81 | CYP1A2 (0.45) | CYP1A2SMN1; SMN2NSD2LMNAFABP5 | |
| SCHEMBL27550728 | 0.79 | CYP19A1 (0.44) | CYP19A1SMN1; SMN2TSHRMAPK1KMT2A | |
| SCHEMBL27810074 | 0.77 | MAPT (0.49) | CYP19A1SMN1; SMN2TSHRMAPK1KMT2A | |
| SCHEMBL10439987 | 0.77 | HSD17B10 (0.46) | SMN1; SMN2KMT2AL3MBTL1LMNAKDM4E | |
| SCHEMBL17199398 | 0.77 | MAPT (0.54) | CYP1A2SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL29380815 | 0.76 | NCF1 (0.47) | CYP1A2SMN1; SMN2LMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531700-A | Mesoionic compounds | 日本化药株式会社 | 2018-01-02 | — | — | CN | disclosed |